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Discovering the Active Ingredients of Medicine and Food Homologous Substances for Inhibiting the Cyclooxygenase-2 Metabolic Pathway by Machine Learning Algorithms

Cyclooxygenase-2 (COX-2) and microsomal prostaglandin E(2) synthase (mPGES-1) are two key targets in anti-inflammatory therapy. Medicine and food homology (MFH) substances have both edible and medicinal properties, providing a valuable resource for the development of novel, safe, and efficient COX-2...

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Detalles Bibliográficos
Autores principales: Tian, Yujia, Zhang, Zhixing, Yan, Aixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574661/
https://www.ncbi.nlm.nih.gov/pubmed/37836625
http://dx.doi.org/10.3390/molecules28196782