Novel 1,2,3-Triazole-Containing Quinoline–Benzimidazole Hybrids: Synthesis, Antiproliferative Activity, In Silico ADME Predictions, and Docking

The newly synthesized quinoline–benzimidazole hybrids containing two types of triazole-methyl-phenoxy linkers were characterized via NMR and elemental analysis. Additional derivatization was achieved by introducing bromine at the C-2 position of the phenoxy core. These novel hybrids were tested for...

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Detalles Bibliográficos
Autores principales: Krstulović, Luka, Mišković Špoljarić, Katarina, Rastija, Vesna, Filipović, Nikolina, Bajić, Miroslav, Glavaš-Obrovac, Ljubica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574761/
https://www.ncbi.nlm.nih.gov/pubmed/37836794
http://dx.doi.org/10.3390/molecules28196950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574761/
https://www.ncbi.nlm.nih.gov/pubmed/37836794
http://dx.doi.org/10.3390/molecules28196950

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