Massive Solubility Changes in Neuronal Proteins upon Simulated Traumatic Brain Injury Reveal the Role of Shockwaves in Irreversible Damage

We investigated the immediate molecular consequences of traumatic brain injuries (TBIs) using a novel proteomics approach. We simulated TBIs using an innovative laboratory apparatus that employed a 5.1 kg dummy head that held neuronal cells and generated a ≤4000 g-force acceleration upon impact. A P...

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Detalles Bibliográficos
Autores principales: Saei, Amir Ata, Gharibi, Hassan, Lyu, Hezheng, Nilsson, Brady, Jafari, Maryam, Von Holst, Hans, Zubarev, Roman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574794/
https://www.ncbi.nlm.nih.gov/pubmed/37836614
http://dx.doi.org/10.3390/molecules28196768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574794/
https://www.ncbi.nlm.nih.gov/pubmed/37836614
http://dx.doi.org/10.3390/molecules28196768

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