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Increasing Neurofilament and Glial Fibrillary Acidic Protein After Treatment Discontinuation Predicts Multiple Sclerosis Disease Activity

BACKGROUND AND OBJECTIVES: Stable patients with multiple sclerosis (MS) may discontinue treatment, but the risk of disease activity is unknown. Serum neurofilament light chain (sNfL) and serum glial fibrillary acidic protein (sGFAP) are biomarkers of subclinical disease activity and may help risk st...

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Detalles Bibliográficos
Autores principales: Bose, Gauruv, Healy, Brian C., Saxena, Shrishti, Saleh, Fermisk, Glanz, Bonnie I., Bakshi, Rohit, Weiner, Howard L., Chitnis, Tanuja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574823/
https://www.ncbi.nlm.nih.gov/pubmed/37813595
http://dx.doi.org/10.1212/NXI.0000000000200167