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Atomic structure of the open SARS-CoV-2 E viroporin

The envelope (E) protein of the SARS-CoV-2 virus forms cation-conducting channels in the endoplasmic reticulum Golgi intermediate compartment (ERGIC) of infected cells. The calcium channel activity of E is associated with the inflammatory responses of COVID-19. Using solid-state NMR (ssNMR) spectros...

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Detalles Bibliográficos
Autores principales: Medeiros-Silva, João, Dregni, Aurelio J., Somberg, Noah H., Duan, Pu, Hong, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575589/
https://www.ncbi.nlm.nih.gov/pubmed/37831764
http://dx.doi.org/10.1126/sciadv.adi9007