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CFTR-rich ionocytes mediate chloride absorption across airway epithelia

The volume and composition of a thin layer of liquid covering the airway surface defend the lung from inhaled pathogens and debris. Airway epithelia secrete Cl(–) into the airway surface liquid through cystic fibrosis transmembrane conductance regulator (CFTR) channels, thereby increasing the volume...

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Detalles Bibliográficos
Autores principales: Lei, Lei, Traore, Soumba, Romano Ibarra, Guillermo S., Karp, Philip H., Rehman, Tayyab, Meyerholz, David K., Zabner, Joseph, Stoltz, David A., Sinn, Patrick L., Welsh, Michael J., McCray, Paul B., Thornell, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575720/
https://www.ncbi.nlm.nih.gov/pubmed/37581935
http://dx.doi.org/10.1172/JCI171268