The CTBP2-PCIF1 complex regulates m(6)Am modification of mRNA in head and neck squamous cell carcinoma

PCIF1 can mediate the methylation of N(6),2′-O-dimethyladenosine (m(6)Am) in mRNA. Yet, the detailed interplay between PCIF1 and the potential cofactors and its pathological significance remain elusive. Here, we demonstrated that PCIF1-mediated cap mRNA m(6)Am modification promoted head and neck squ...

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Detalles Bibliográficos
Autores principales: Li, Kang, Chen, Jie, Zhang, Caihua, Cheng, Maosheng, Chen, Shuang, Song, Wei, Yang, Chunlong, Ling, Rongsong, Chen, Zhi, Wang, Xiaochen, Xiong, Gan, Ma, Jieyi, Zhu, Yan, Yuan, Quan, Liu, Qi, Peng, Liang, Chen, Qianming, Chen, Demeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575729/
https://www.ncbi.nlm.nih.gov/pubmed/37643007
http://dx.doi.org/10.1172/JCI170173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575729/
https://www.ncbi.nlm.nih.gov/pubmed/37643007
http://dx.doi.org/10.1172/JCI170173

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