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Hypertonic saline induces inflammation in human macrophages through the NLRP1 inflammasome

Nebulized hypertonic saline (3–7%) is commonly used to increase mucociliary clearance in patients with chronic airway disease and/or virus infections. However, altered salt concentrations may contribute to inflammatory responses. The aim of this study was to investigate whether 500 mM NaCl (3%) trig...

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Detalles Bibliográficos
Autores principales: Sposito, Francesca, Northey, Sarah, Charras, Amandine, McNamara, Paul S., Hedrich, Christian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575766/
https://www.ncbi.nlm.nih.gov/pubmed/37573430
http://dx.doi.org/10.1038/s41435-023-00218-7