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Striatal dopaminergic alterations in individuals with copy number variants at the 22q11.2 genetic locus and their implications for psychosis risk: a [18F]-DOPA PET study

Dopaminergic dysregulation is one of the leading hypotheses for the pathoetiology underlying psychotic disorders such as schizophrenia. Molecular imaging studies have shown increased striatal dopamine synthesis capacity (DSC) in schizophrenia and people in the prodrome of psychosis. However, it is u...

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Detalles Bibliográficos
Autores principales: Rogdaki, Maria, Devroye, Céline, Ciampoli, Mariasole, Veronese, Mattia, Ashok, Abhishekh H., McCutcheon, Robert A., Jauhar, Sameer, Bonoldi, Ilaria, Gudbrandsen, Maria, Daly, Eileen, van Amelsvoort, Therese, Van Den Bree, Marianne, Owen, Michael J., Turkheimer, Federico, Papaleo, Francesco, Howes, Oliver D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575769/
https://www.ncbi.nlm.nih.gov/pubmed/33981004
http://dx.doi.org/10.1038/s41380-021-01108-y