IL-2 immunotherapy for targeting regulatory T cells in autoimmunity

FOXP3(+) regulatory T cells (T(reg)) are indispensable for immune homoeostasis and for the prevention of autoimmune diseases. Interleukin-2 (IL-2) signalling is critical in all aspects of T(reg) biology. Consequences of defective IL-2 signalling are insufficient numbers or dysfunction of T(reg) and...

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Detalles Bibliográficos
Autores principales: Lykhopiy, Valentina, Malviya, Vanshika, Humblet-Baron, Stephanie, Schlenner, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575774/
https://www.ncbi.nlm.nih.gov/pubmed/37741949
http://dx.doi.org/10.1038/s41435-023-00221-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575774/
https://www.ncbi.nlm.nih.gov/pubmed/37741949
http://dx.doi.org/10.1038/s41435-023-00221-y

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