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Characterization of early psychosis patients carrying a genetic vulnerability to redox dysregulation: a computational analysis of mechanism-based gene expression profile in fibroblasts

In view of its heterogeneity, schizophrenia needs new diagnostic tools based on mechanistic biomarkers that would allow early detection. Complex interaction between genetic and environmental risk factors may lead to NMDAR hypofunction, inflammation and redox dysregulation, all converging on oxidativ...

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Detalles Bibliográficos
Autores principales: Giangreco, Basilio, Dwir, Daniella, Klauser, Paul, Jenni, Raoul, Golay, Philippe, Cleusix, Martine, Baumann, Philipp S., Cuénod, Michel, Conus, Philippe, Toni, Nicolas, Do, Kim Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575782/
https://www.ncbi.nlm.nih.gov/pubmed/37002404
http://dx.doi.org/10.1038/s41380-023-02034-x