An old model with new insights: endogenous retroviruses drive the evolvement toward ASD susceptibility and hijack transcription machinery during development

The BTBR T(+)Itpr3(tf)/J (BTBR/J) strain is one of the most valid models of idiopathic autism, serving as a potent forward genetics tool to dissect the complexity of autism. We found that a sister strain with an intact corpus callosum, BTBR TF/ArtRbrc (BTBR/R), showed more prominent autism core symp...

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Detalles Bibliográficos
Autores principales: Lin, Chia-Wen, Ellegood, Jacob, Tamada, Kota, Miura, Ikuo, Konda, Mikiko, Takeshita, Kozue, Atarashi, Koji, Lerch, Jason P., Wakana, Shigeharu, McHugh, Thomas J., Takumi, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Immediate Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575786/
https://www.ncbi.nlm.nih.gov/pubmed/36882500
http://dx.doi.org/10.1038/s41380-023-01999-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575786/
https://www.ncbi.nlm.nih.gov/pubmed/36882500
http://dx.doi.org/10.1038/s41380-023-01999-z

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