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Subcellular distribution of the rAAV genome depends on genome structure

Many studies have been conducted on the transduction efficiency of recombinant adeno-associated virus (rAAV) depending on the serotype and genome structure, such as single-stranded (ss) and self-complementary (sc). To understand the variation in therapeutic efficacy, we focused on investigating subc...

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Detalles Bibliográficos
Autores principales: Oh, Nuri, Tarte, Naresh H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575858/
https://www.ncbi.nlm.nih.gov/pubmed/37833341
http://dx.doi.org/10.1038/s41598-023-44074-x