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Mercaptonicotinic acid activated thiolated chitosan (MNA-TG-chitosan) to enable peptide oral delivery by opening cell tight junctions and enhancing transepithelial transport
Recent advances in peptide delivery and nanotechnology has resulted in emergence of several non-parenteral administration routes that replace subcutaneous injections associated with patient discomfort. Thiolated biopolymers are relatively new materials being explored to enhance mucoadhesivity and pe...
Autores principales: | Pratap-Singh, Anubhav, Guo, Yigong, Baldelli, Alberto, Singh, Anika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575883/ https://www.ncbi.nlm.nih.gov/pubmed/37833426 http://dx.doi.org/10.1038/s41598-023-44178-4 |
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