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Alkaline shear-thinning micro-nanocomposite hydrogels initiate endogenous TGFβ signaling for in situ bone regeneration

Recruiting endogenous stem cells to bone defects without stem cell transplantation and exogenous factor delivery represents a promising strategy for bone regeneration. Herein, we develop an alkaline shear-thinning micro-nanocomposite hydrogel (10-MmN), aiming to alkaline-activate endogenous TGFβ1 an...

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Detalles Bibliográficos
Autores principales: Niu, Yuting, Yang, Zhen, Yang, Yang, Wang, Xu, Zhang, Ping, Lv, Longwei, Wang, Sainan, Liu, Yan, Liu, Yunsong, Zhou, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575889/
https://www.ncbi.nlm.nih.gov/pubmed/37833374
http://dx.doi.org/10.1038/s41536-023-00333-z