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Design of experiment-oriented development of solvent-free mixed micellar chromatographic method for concomitant determination of metronidazole and ciprofloxacin hydrochloride

A green, fast and robust solvent-free chromatographic method has been developed for concomitant analysis of ciprofloxacin HCl and metronidazole in bulk powder as well as in dosage form using levofloxacin as internal standard (I.S.). Two different designs including fractional factorial (FFD) and Box–...

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Detalles Bibliográficos
Autores principales: Hammad, Sherin F., Habib, Ahmed A., Kamal, Amira H., Megahed, Safa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575926/
https://www.ncbi.nlm.nih.gov/pubmed/37833422
http://dx.doi.org/10.1038/s41598-023-44498-5