Bile acids-mediated intracellular cholesterol transport promotes intestinal cholesterol absorption and NPC1L1 recycling

Niemann-Pick C1-like 1 (NPC1L1) is essential for intestinal cholesterol absorption. Together with the cholesterol-rich and Flotillin-positive membrane microdomain, NPC1L1 is internalized via clathrin-mediated endocytosis and transported to endocytic recycling compartment (ERC). When ERC cholesterol...

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Detalles Bibliográficos
Autores principales: Xiao, Jian, Dong, Le-Wei, Liu, Shuai, Meng, Fan-Hua, Xie, Chang, Lu, Xiao-Yi, Zhang, Weiping J., Luo, Jie, Song, Bao-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575946/
https://www.ncbi.nlm.nih.gov/pubmed/37833289
http://dx.doi.org/10.1038/s41467-023-42179-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575946/
https://www.ncbi.nlm.nih.gov/pubmed/37833289
http://dx.doi.org/10.1038/s41467-023-42179-5

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