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Structural basis for triacylglyceride extraction from mycobacterial inner membrane by MFS transporter Rv1410

Mycobacterium tuberculosis is protected from antibiotic therapy by a multi-layered hydrophobic cell envelope. Major facilitator superfamily (MFS) transporter Rv1410 and the periplasmic lipoprotein LprG are involved in transport of triacylglycerides (TAGs) that seal the mycomembrane. Here, we report...

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Detalles Bibliográficos
Autores principales: Remm, Sille, De Vecchis, Dario, Schöppe, Jendrik, Hutter, Cedric A. J., Gonda, Imre, Hohl, Michael, Newstead, Simon, Schäfer, Lars V., Seeger, Markus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576003/
https://www.ncbi.nlm.nih.gov/pubmed/37833269
http://dx.doi.org/10.1038/s41467-023-42073-0