Cargando…
Structural basis for triacylglyceride extraction from mycobacterial inner membrane by MFS transporter Rv1410
Mycobacterium tuberculosis is protected from antibiotic therapy by a multi-layered hydrophobic cell envelope. Major facilitator superfamily (MFS) transporter Rv1410 and the periplasmic lipoprotein LprG are involved in transport of triacylglycerides (TAGs) that seal the mycomembrane. Here, we report...
Autores principales: | Remm, Sille, De Vecchis, Dario, Schöppe, Jendrik, Hutter, Cedric A. J., Gonda, Imre, Hohl, Michael, Newstead, Simon, Schäfer, Lars V., Seeger, Markus A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576003/ https://www.ncbi.nlm.nih.gov/pubmed/37833269 http://dx.doi.org/10.1038/s41467-023-42073-0 |
Ejemplares similares
-
Increased drug permeability of a stiffened mycobacterial outer membrane in cells lacking MFS transporter Rv1410 and lipoprotein LprG
por: Hohl, Michael, et al.
Publicado: (2019) -
Mycobacterial Metabolic Syndrome: LprG and Rv1410 Regulate Triacylglyceride Levels, Growth Rate and Virulence in Mycobacterium tuberculosis
por: Martinot, Amanda J., et al.
Publicado: (2016) -
A uniform cloning platform for mycobacterial genetics and protein production
por: Arnold, Fabian M., et al.
Publicado: (2018) -
Investigation of the Rv3065, Rv2942, Rv1258c, Rv1410c, and Rv2459 efflux pump genes expression among multidrug-resistant Mycobacterium tuberculosis clinical isolates
por: Shahi, Fatemeh, et al.
Publicado: (2021) -
The Ketogenic Effect of Medium-Chain Triacylglycerides
por: Lin, Ting-Yu, et al.
Publicado: (2021)