Assessing MAPPs assay as a tool to predict the immunogenicity potential of protein therapeutics

MHC-II-associated peptide proteomics (MAPPs) is a mass spectrometry-based (MS) method to identify naturally presented MHC-II-associated peptides that could elicit CD4+T cell activation. MAPPs assay is considered one of the assays that better characterize the safety of biotherapeutics by driving the...

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Detalles Bibliográficos
Autores principales: Di Ianni, Andrea, Fraone, Tiziana, Balestra, Piercesare, Cowan, Kyra, Riccardi Sirtori, Federico, Barbero, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576005/
https://www.ncbi.nlm.nih.gov/pubmed/37833075
http://dx.doi.org/10.26508/lsa.202302095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576005/
https://www.ncbi.nlm.nih.gov/pubmed/37833075
http://dx.doi.org/10.26508/lsa.202302095

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