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Assessing MAPPs assay as a tool to predict the immunogenicity potential of protein therapeutics
MHC-II-associated peptide proteomics (MAPPs) is a mass spectrometry-based (MS) method to identify naturally presented MHC-II-associated peptides that could elicit CD4+T cell activation. MAPPs assay is considered one of the assays that better characterize the safety of biotherapeutics by driving the...
Autores principales: | Di Ianni, Andrea, Fraone, Tiziana, Balestra, Piercesare, Cowan, Kyra, Riccardi Sirtori, Federico, Barbero, Luca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576005/ https://www.ncbi.nlm.nih.gov/pubmed/37833075 http://dx.doi.org/10.26508/lsa.202302095 |
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