Rewiring of the promoter-enhancer interactome and regulatory landscape in glioblastoma orchestrates gene expression underlying neurogliomal synaptic communication

Chromatin organization controls transcription by modulating 3D-interactions between enhancers and promoters in the nucleus. Alterations in epigenetic states and 3D-chromatin organization result in gene expression changes contributing to cancer. Here, we map the promoter-enhancer interactome and regu...

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Detalles Bibliográficos
Autores principales: Chakraborty, Chaitali, Nissen, Itzel, Vincent, Craig A., Hägglund, Anna-Carin, Hörnblad, Andreas, Remeseiro, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576091/
https://www.ncbi.nlm.nih.gov/pubmed/37833281
http://dx.doi.org/10.1038/s41467-023-41919-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576091/
https://www.ncbi.nlm.nih.gov/pubmed/37833281
http://dx.doi.org/10.1038/s41467-023-41919-x

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