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The inhibitory mechanism of a small protein reveals its role in antimicrobial peptide sensing

A large number of small membrane proteins have been uncovered in bacteria, but their mechanism of action has remained mostly elusive. Here, we investigate the mechanism of a physiologically important small protein, MgrB, which represses the activity of the sensor kinase PhoQ and is widely distribute...

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Detalles Bibliográficos
Autores principales: Jiang, Shan, Steup, Lydia C., Kippnich, Charlotte, Lazaridi, Symela, Malengo, Gabriele, Lemmin, Thomas, Yuan, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576120/
https://www.ncbi.nlm.nih.gov/pubmed/37792514
http://dx.doi.org/10.1073/pnas.2309607120