Cargando…

Characteristics and anatomic location of PD-1(+)TCF1(+) stem-like CD8 T cells in chronic viral infection and cancer

CD8 T cells play an essential role in antitumor immunity and chronic viral infections. Recent findings have delineated the differentiation pathway of CD8 T cells in accordance with the progenitor-progeny relationship of TCF1(+) stem-like and Tim-3(+)TCF1(−) more differentiated T cells. Here, we inve...

Descripción completa

Detalles Bibliográficos
Autores principales: Im, Se Jin, Obeng, Rebecca C., Nasti, Tahseen H., McManus, Daniel, Kamphorst, Alice O., Gunisetty, Sivaram, Prokhnevska, Nataliya, Carlisle, Jennifer W., Yu, Ke, Sica, Gabriel L., Cardozo, Lucas E., Gonçalves, André N. A., Kissick, Haydn T., Nakaya, Helder I., Ramalingam, Suresh S., Ahmed, Rafi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576122/
https://www.ncbi.nlm.nih.gov/pubmed/37782797
http://dx.doi.org/10.1073/pnas.2221985120