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A Type 1 Diabetes Polygenic Score Is Not Associated With Prevalent Type 2 Diabetes in Large Population Studies
CONTEXT: Both type 1 diabetes (T1D) and type 2 diabetes (T2D) have significant genetic contributions to risk and understanding their overlap can offer clinical insight. OBJECTIVE: We examined whether a T1D polygenic score (PS) was associated with a diagnosis of T2D in the Cohorts for Heart and Aging...
Autores principales: | Srinivasan, Shylaja, Wu, Peitao, Mercader, Josep M, Udler, Miriam S, Porneala, Bianca C, Bartz, Traci M, Floyd, James S, Sitlani, Colleen, Guo, Xiquing, Haessler, Jeffrey, Kooperberg, Charles, Liu, Jun, Ahmad, Shahzad, van Duijn, Cornelia, Liu, Ching-Ti, Goodarzi, Mark O, Florez, Jose C, Meigs, James B, Rotter, Jerome I, Rich, Stephen S, Dupuis, Josée, Leong, Aaron |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576255/ https://www.ncbi.nlm.nih.gov/pubmed/37841955 http://dx.doi.org/10.1210/jendso/bvad123 |
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