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Molecular mechanism of vimentin nuclear localization associated with the migration and invasion of daughter cells derived from polyploid giant cancer cells

BACKGROUND: Polyploid giant cancer cells (PGCCs), a specific type of cancer stem cells (CSCs), can be induced by hypoxic microenvironments, chemical reagents, radiotherapy, and Chinese herbal medicine. Moreover, PGCCs can produce daughter cells that undergo epithelial–mesenchymal transition, which l...

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Detalles Bibliográficos
Autores principales: Fan, Linlin, Zheng, Minying, Zhou, Xinyue, Yu, Yongjun, Ning, Yidi, Fu, Wenzheng, Xu, Jing, Zhang, Shiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576317/
https://www.ncbi.nlm.nih.gov/pubmed/37833712
http://dx.doi.org/10.1186/s12967-023-04585-7