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Pax7 haploinsufficiency impairs muscle stem cell function in Cre-recombinase mice and underscores the importance of appropriate controls

Ever since its introduction as a genetic tool, the Cre-lox system has been widely used for molecular genetic studies in vivo in the context of health and disease, as it allows time- and cell-specific gene modifications. However, insertion of the Cre-recombinase cassette in the gene of interest can a...

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Detalles Bibliográficos
Autores principales: Mademtzoglou, Despoina, Geara, Perla, Mourikis, Philippos, Relaix, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576335/
https://www.ncbi.nlm.nih.gov/pubmed/37833800
http://dx.doi.org/10.1186/s13287-023-03506-1