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Pax7 haploinsufficiency impairs muscle stem cell function in Cre-recombinase mice and underscores the importance of appropriate controls
Ever since its introduction as a genetic tool, the Cre-lox system has been widely used for molecular genetic studies in vivo in the context of health and disease, as it allows time- and cell-specific gene modifications. However, insertion of the Cre-recombinase cassette in the gene of interest can a...
Autores principales: | Mademtzoglou, Despoina, Geara, Perla, Mourikis, Philippos, Relaix, Frederic |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576335/ https://www.ncbi.nlm.nih.gov/pubmed/37833800 http://dx.doi.org/10.1186/s13287-023-03506-1 |
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