Behavioral and neuropathological characterization over the adult lifespan of the human tau knock-in mouse

Tau is a microtubule-associated protein with a diverse functional repertoire linked to neurodegenerative disease. Recently, a human tau knock-in (MAPT KI) mouse was developed that may overcome many limitations associated with current animal models used to study tau. In MAPT KI mice, the entire murin...

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Detalles Bibliográficos
Autores principales: Benskey, Matthew J., Panoushek, Spencer, Saito, Takashi, Saido, Takaomi C., Grabinski, Tessa, Kanaan, Nicholas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576558/
https://www.ncbi.nlm.nih.gov/pubmed/37842124
http://dx.doi.org/10.3389/fnagi.2023.1265151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576558/
https://www.ncbi.nlm.nih.gov/pubmed/37842124
http://dx.doi.org/10.3389/fnagi.2023.1265151

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