pLM-BLAST: distant homology detection based on direct comparison of sequence representations from protein language models

MOTIVATION: The detection of homology through sequence comparison is a typical first step in the study of protein function and evolution. In this work, we explore the applicability of protein language models to this task. RESULTS: We introduce pLM-BLAST, a tool inspired by BLAST, that detects distan...

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Detalles Bibliográficos
Autores principales: Kaminski, Kamil, Ludwiczak, Jan, Pawlicki, Kamil, Alva, Vikram, Dunin-Horkawicz, Stanislaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576641/
https://www.ncbi.nlm.nih.gov/pubmed/37725369
http://dx.doi.org/10.1093/bioinformatics/btad579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576641/
https://www.ncbi.nlm.nih.gov/pubmed/37725369
http://dx.doi.org/10.1093/bioinformatics/btad579

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