Cargando…
pLM-BLAST: distant homology detection based on direct comparison of sequence representations from protein language models
MOTIVATION: The detection of homology through sequence comparison is a typical first step in the study of protein function and evolution. In this work, we explore the applicability of protein language models to this task. RESULTS: We introduce pLM-BLAST, a tool inspired by BLAST, that detects distan...
Autores principales: | Kaminski, Kamil, Ludwiczak, Jan, Pawlicki, Kamil, Alva, Vikram, Dunin-Horkawicz, Stanislaw |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576641/ https://www.ncbi.nlm.nih.gov/pubmed/37725369 http://dx.doi.org/10.1093/bioinformatics/btad579 |
Ejemplares similares
-
Rossmann-toolbox: a deep learning-based protocol for the prediction and design of cofactor specificity in Rossmann fold proteins
por: Kamiński, Kamil, et al.
Publicado: (2021) -
PiPred – a deep-learning method for prediction of π-helices in protein sequences
por: Ludwiczak, Jan, et al.
Publicado: (2019) -
localpdb—a Python package to manage protein structures and their annotations
por: Ludwiczak, Jan, et al.
Publicado: (2022) -
Multicad Support in CERN's PLM
por: Ansel, Antoine, et al.
Publicado: (2022) -
Heat Resistance Mediated by pLM58 Plasmid-Borne ClpL in Listeria monocytogenes
por: Pöntinen, Anna, et al.
Publicado: (2017)