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Presymptomatic geographical distribution of ALS patients suggests the involvement of environmental factors in the disease pathogenesis

BACKGROUND: Given that the pathogenetic process of ALS begins many years prior to its clinical onset, examining patients’ residential histories may offer insights on the disease risk factors. Here, we analyzed the spatial distribution of a large ALS cohort in the 50 years preceding the disease onset...

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Detalles Bibliográficos
Autores principales: Vasta, Rosario, Callegaro, S., Sgambetterra, S., Cabras, S., Di Pede, F., De Mattei, F., Matteoni, E., Grassano, M., Bombaci, A., De Marco, G., Fuda, G., Marchese, G., Palumbo, F., Canosa, A., Mazzini, L., De Marchi, F., Moglia, C., Manera, U., Chiò, A., Calvo, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576667/
https://www.ncbi.nlm.nih.gov/pubmed/37491680
http://dx.doi.org/10.1007/s00415-023-11888-8