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Presymptomatic geographical distribution of ALS patients suggests the involvement of environmental factors in the disease pathogenesis
BACKGROUND: Given that the pathogenetic process of ALS begins many years prior to its clinical onset, examining patients’ residential histories may offer insights on the disease risk factors. Here, we analyzed the spatial distribution of a large ALS cohort in the 50 years preceding the disease onset...
Autores principales: | Vasta, Rosario, Callegaro, S., Sgambetterra, S., Cabras, S., Di Pede, F., De Mattei, F., Matteoni, E., Grassano, M., Bombaci, A., De Marco, G., Fuda, G., Marchese, G., Palumbo, F., Canosa, A., Mazzini, L., De Marchi, F., Moglia, C., Manera, U., Chiò, A., Calvo, A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576667/ https://www.ncbi.nlm.nih.gov/pubmed/37491680 http://dx.doi.org/10.1007/s00415-023-11888-8 |
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