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Quantitative analysis of gastrointestinal fluid absorption and secretion to estimate luminal fluid dynamics in rats

The drug absorption profile is dependent on the luminal drug concentration, which in turn is influenced by the gastrointestinal (GI) fluid dynamics. In the present study, therefore, we aimed to examine the luminal fluid dynamics by kinetically analyzing fluid absorption and secretion along the GI tr...

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Detalles Bibliográficos
Autores principales: Funai, Yuta, Ichijo, Kazuki, Suzuki, Satoru, Tateishi, Yuta, Inoue, Katsuhisa, Tamai, Ikumi, Shirasaka, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576741/
https://www.ncbi.nlm.nih.gov/pubmed/37838772
http://dx.doi.org/10.1038/s41598-023-44742-y