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Stochastic gene expression and environmental stressors trigger variable somite segmentation phenotypes
Mutations of several genes cause incomplete penetrance and variable expressivity of phenotypes, which are usually attributed to modifier genes or gene-environment interactions. Here, we show stochastic gene expression underlies the variability of somite segmentation defects in embryos mutant for seg...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576776/ https://www.ncbi.nlm.nih.gov/pubmed/37838784 http://dx.doi.org/10.1038/s41467-023-42220-7 |