Stochastic gene expression and environmental stressors trigger variable somite segmentation phenotypes

Mutations of several genes cause incomplete penetrance and variable expressivity of phenotypes, which are usually attributed to modifier genes or gene-environment interactions. Here, we show stochastic gene expression underlies the variability of somite segmentation defects in embryos mutant for seg...

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Detalles Bibliográficos
Autores principales: Keseroglu, Kemal, Zinani, Oriana Q. H., Keskin, Sevdenur, Seawall, Hannah, Alpay, Eslim E., Özbudak, Ertuğrul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576776/
https://www.ncbi.nlm.nih.gov/pubmed/37838784
http://dx.doi.org/10.1038/s41467-023-42220-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576776/
https://www.ncbi.nlm.nih.gov/pubmed/37838784
http://dx.doi.org/10.1038/s41467-023-42220-7

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