Extracellular vesicles from subjects with COPD modulate cancer initiating cells phenotype through HIF-1α shuttling

Chronic obstructive pulmonary disease (COPD) is a risk factor for lung cancer development. COPD induces activation of hypoxia-induced signaling, causing remodeling of surrounding microenvironmental cells also modulating the release and cargo of their extracellular vesicles (EVs). We aimed to evaluat...

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Detalles Bibliográficos
Autores principales: Petraroia, Ilaria, Ghidotti, Patrizia, Bertolini, Giulia, Pontis, Francesca, Roz, Luca, Balsamo, Melissa, Suatoni, Paola, Pastorino, Ugo, Ferretti, Anna Maria, Sozzi, Gabriella, Fortunato, Orazio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576796/
https://www.ncbi.nlm.nih.gov/pubmed/37838700
http://dx.doi.org/10.1038/s41419-023-06212-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576796/
https://www.ncbi.nlm.nih.gov/pubmed/37838700
http://dx.doi.org/10.1038/s41419-023-06212-1

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