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FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation

Exocrine acinar cells in salivary glands (SG) are critical for oral health and loss of functional acinar cells is a major clinical challenge. Fibroblast growth factor receptors (FGFR) are essential for early development of multiple organs, including SG. However, the role of FGFR signaling in specifi...

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Detalles Bibliográficos
Autores principales: Aure, Marit H., Symonds, Jennifer M., Villapudua, Carlos U., Dodge, Joshua T., Werner, Sabine, Knosp, Wendy M., Hoffman, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576811/
https://www.ncbi.nlm.nih.gov/pubmed/37838739
http://dx.doi.org/10.1038/s41467-023-42243-0