Cargando…

Bringing cell therapy to tumors: considerations for optimal CAR binder design

Chimeric antigen receptor (CAR)-T cells have revolutionized the immunotherapy of B-cell malignancies and are poised to expand the range of their impact across a broad range of oncology and non-oncology indications. Critical to the success of a given CAR is the choice of binding domain, as this is th...

Descripción completa

Detalles Bibliográficos
Autor principal: Smith, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576856/
https://www.ncbi.nlm.nih.gov/pubmed/37846297
http://dx.doi.org/10.1093/abt/tbad019