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In vivo retinal imaging is associated with cognitive decline, blood-brain barrier disruption and neuroinflammation in type 2 diabetic mice

INTRODUCTION: Type 2 diabetes (T2D) is associated with chronic inflammation and neurovascular changes that lead to functional impairment and atrophy in neural-derived tissue. A reduction in retinal thickness is an early indicator of diabetic retinopathy (DR), with progressive loss of neuroglia corre...

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Detalles Bibliográficos
Autores principales: Majimbi, May, McLenachan, Samuel, Nesbit, Michael, Chen, Fred K., Lam, Virginie, Mamo, John, Takechi, Ryu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577437/
https://www.ncbi.nlm.nih.gov/pubmed/37850093
http://dx.doi.org/10.3389/fendo.2023.1224418