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Neuritin affects the activity of neuralized-like 1 by promoting degradation and weakening its affinity for substrate: Neuritin regulates the activity of the E3 ligase NEURL1

Neuritin plays a key role in neural development and regeneration by promoting neurite outgrowth and synapse maturation. Our previous research revealed the mechanism by which neuritin inhibits Notch signaling through interaction with neuralized-like 1 (Neurl1) to promote neurite growth. However, how...

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Detalles Bibliográficos
Autores principales: Zhu, Jingling, Li, Yu, Zhong, Chen, Zhu, Meiyi, Zheng, Yan, Xiong, Anying, Meng, Pingping, Shan, Liya, Li, Yang, Huang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577452/
https://www.ncbi.nlm.nih.gov/pubmed/37249336
http://dx.doi.org/10.3724/abbs.2023098