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Neuritin affects the activity of neuralized-like 1 by promoting degradation and weakening its affinity for substrate: Neuritin regulates the activity of the E3 ligase NEURL1
Neuritin plays a key role in neural development and regeneration by promoting neurite outgrowth and synapse maturation. Our previous research revealed the mechanism by which neuritin inhibits Notch signaling through interaction with neuralized-like 1 (Neurl1) to promote neurite growth. However, how...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577452/ https://www.ncbi.nlm.nih.gov/pubmed/37249336 http://dx.doi.org/10.3724/abbs.2023098 |