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Cryo-EM of α-tubulin isotype-containing microtubules revealed a contracted structure of α4A/β2A microtubules: α4A/β2A microtubules display contracted lattices

Microtubules are hollow α/β-tubulin heterodimeric polymers that play critical roles in cells. In vertebrates, both α- and β-tubulins have multiple isotypes encoded by different genes, which are intrinsic factors in regulating microtubule functions. However, the structures of microtubules composed of...

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Detalles Bibliográficos
Autores principales: Diao, Lei, Zheng, Wei, Zhao, Qiaoyu, Liu, Mingyi, Fu, Zhenglin, Zhang, Xu, Bao, Lan, Cong, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577476/
https://www.ncbi.nlm.nih.gov/pubmed/37439022
http://dx.doi.org/10.3724/abbs.2023130