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AAV‐Mediated nuclear localized PGC1α4 delivery in muscle ameliorates sarcopenia and aging‐associated metabolic dysfunctions

Sarcopenia is characterized of muscle mass loss and functional decline in elder individuals which severely affects human physical activity, metabolic homeostasis, and life quality. Physical exercise is considered effective in combating muscle atrophy and sarcopenia, yet it is not feasible to elders...

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Detalles Bibliográficos
Autores principales: Guo, Mingwei, Zhang, Jun, Ma, Ying, Zhu, Zhenzhong, Zuo, Hui, Yao, Jing, Wu, Xia, Wang, Dongmei, Yu, Jian, Meng, Meiyao, Liu, Caizhi, Zhang, Yi, Chen, Jiangrong, Lu, Jian, Ding, Shuzhe, Hu, Cheng, Ma, Xinran, Xu, Lingyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577532/
https://www.ncbi.nlm.nih.gov/pubmed/37584432
http://dx.doi.org/10.1111/acel.13961