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Targeted sequencing of the 9p21.3 region reveals association with reduced disease risks in Ashkenazi Jewish centenarians

Genome‐wide association studies (GWAS) have pinpointed the chromosomal locus 9p21.3 as a genetic hotspot for various age‐related disorders. Common genetic variants in this locus are linked to multiple traits, including coronary artery diseases, cancers, and diabetes. Centenarians are known for their...

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Detalles Bibliográficos
Autores principales: Zhu, Yizhou, Ryu, Seungjin, Tare, Archana, Barzilai, Nir, Atzmon, Gil, Suh, Yousin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577543/
https://www.ncbi.nlm.nih.gov/pubmed/37605876
http://dx.doi.org/10.1111/acel.13962