Bloom syndrome patients and mice display accelerated epigenetic aging

Bloom syndrome (BSyn) is an autosomal recessive disorder caused by variants in the BLM gene, which is involved in genome stability. Patients with BSyn present with poor growth, sun sensitivity, mild immunodeficiency, diabetes, and increased risk of cancer, most commonly leukemias. Interestingly, pat...

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Detalles Bibliográficos
Autores principales: Lee, Jamie, Zhang, Joshua, Flanagan, Maeve, Martinez, Julian A., Cunniff, Christopher, Kucine, Nicole, Lu, Ake T., Haghani, Amin, Gordevičius, Juozas, Horvath, Steve, Chang, Vivian Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577546/
https://www.ncbi.nlm.nih.gov/pubmed/37594403
http://dx.doi.org/10.1111/acel.13964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577546/
https://www.ncbi.nlm.nih.gov/pubmed/37594403
http://dx.doi.org/10.1111/acel.13964

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