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Alterations of lipid‐mediated mitophagy result in aging‐dependent sensorimotor defects

The metabolic consequences of mitophagy alterations due to age‐related stress in healthy aging brains versus neurodegeneration remain unknown. Here, we demonstrate that ceramide synthase 1 (CerS1) is transported to the outer mitochondrial membrane by the p17/PERMIT transporter that recognizes misloc...

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Detalles Bibliográficos
Autores principales: Oleinik, Natalia, Albayram, Onder, Kassir, Mohamed Faisal, Atilgan, F. Cansu, Walton, Chase, Karakaya, Eda, Kurtz, John, Alekseyenko, Alexander, Alsudani, Habeeb, Sheridan, Megan, Szulc, Zdzislaw M., Ogretmen, Besim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577547/
https://www.ncbi.nlm.nih.gov/pubmed/37614052
http://dx.doi.org/10.1111/acel.13954