Cargando…
Alterations of lipid‐mediated mitophagy result in aging‐dependent sensorimotor defects
The metabolic consequences of mitophagy alterations due to age‐related stress in healthy aging brains versus neurodegeneration remain unknown. Here, we demonstrate that ceramide synthase 1 (CerS1) is transported to the outer mitochondrial membrane by the p17/PERMIT transporter that recognizes misloc...
Autores principales: | Oleinik, Natalia, Albayram, Onder, Kassir, Mohamed Faisal, Atilgan, F. Cansu, Walton, Chase, Karakaya, Eda, Kurtz, John, Alekseyenko, Alexander, Alsudani, Habeeb, Sheridan, Megan, Szulc, Zdzislaw M., Ogretmen, Besim |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577547/ https://www.ncbi.nlm.nih.gov/pubmed/37614052 http://dx.doi.org/10.1111/acel.13954 |
Ejemplares similares
-
The Role of Ceramide Metabolism and Signaling in the Regulation of Mitophagy and Cancer Therapy
por: Sheridan, Megan, et al.
Publicado: (2021) -
Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis
por: Janneh, Alhaji H., et al.
Publicado: (2022) -
HPV/E7 induces chemotherapy‐mediated tumor suppression by ceramide‐dependent mitophagy
por: Thomas, Raquela J, et al.
Publicado: (2017) -
395 Vascular Cognitive Impairment: Novel Endothelial Mechanisms and the Impact of Dietary PUFAs
por: Tomberlin, Jensen, et al.
Publicado: (2022) -
Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy
por: Sentelle, R. David, et al.
Publicado: (2012)