Heterochromatic silencing of immune‐related genes in glia is required for BBB integrity and normal lifespan in drosophila

Glia and neurons face different challenges in aging and may engage different mechanisms to maintain their morphology and functionality. Here, we report that adult‐onset downregulation of a Drosophila gene CG32529/GLAD led to shortened lifespan and age‐dependent brain degeneration. This regulation ex...

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Detalles Bibliográficos
Autores principales: Shu, Shunpan, Jiang, Mingsheng, Deng, Xue, Yue, Wenkai, Cao, Xu, Zhang, Kai, Wang, Zeqing, He, Hao, Cui, Jihong, Wang, Qiangqiang, Qu, Kun, Fang, Yanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577565/
https://www.ncbi.nlm.nih.gov/pubmed/37594178
http://dx.doi.org/10.1111/acel.13947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577565/
https://www.ncbi.nlm.nih.gov/pubmed/37594178
http://dx.doi.org/10.1111/acel.13947

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