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Pioneer activity distinguishes activating from non‐activating SOX2 binding sites

Genome‐wide transcriptional activity involves the binding of many transcription factors (TFs) to thousands of sites in the genome. Pioneer TFs are a class of TFs that maintain open chromatin and allow non‐pioneer TFs access to their target sites. Determining which TF binding sites directly drive tra...

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Detalles Bibliográficos
Autores principales: Maresca, Michela, van den Brand, Teun, Li, Hangpeng, Teunissen, Hans, Davies, James, de Wit, Elzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577566/
https://www.ncbi.nlm.nih.gov/pubmed/37691488
http://dx.doi.org/10.15252/embj.2022113150