Cargando…

A bifunctional kinase–phosphatase module balances mitotic checkpoint strength and kinetochore–microtubule attachment stability

Two major mechanisms safeguard genome stability during mitosis: the mitotic checkpoint delays mitosis until all chromosomes have attached to microtubules, and the kinetochore–microtubule error‐correction pathway keeps this attachment process free from errors. We demonstrate here that the optimal str...

Descripción completa

Detalles Bibliográficos
Autores principales: Corno, Andrea, Cordeiro, Marilia H, Allan, Lindsey A, Lim, Qian‐Wei, Harrington, Elena, Smith, Richard J, Saurin, Adrian T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577578/
https://www.ncbi.nlm.nih.gov/pubmed/37712330
http://dx.doi.org/10.15252/embj.2022112630